Shadowrun: Razor's Edge
Former cop now on the lam after being accused of murdering her partner.
Shepard was a star in the Academy, excelling in marksmanship and unarmed combat.
After success as a beat cop, she was quickly promoted to a CPS officer. However, shortly after her promotion, her partner (with whom she shared a very strong friendship) was discovered murdered. The evidence clearly pointed to Shepard as the offender.
A corruption deep within CPS set a plan in motion and used her as tool, framing her and setting the hounds on her trail. She knew she would not be able to find justice for her partner if she stayed and played along with the court system, so she decided to take it into her own hands and evade the officers that sought to arrest her for the murder she did not commit.